¹ú¼ÒÒ©¼à¾Ö(NMPA)¹ÙÍø¹«Ê¾ £¬£¬£¬£¬£¬Ñ±Â¹ÉúÎïÉ걨µÄ°ÐÏòBCMA CAR-T²úÆ·ÒÁ»ù°ÂÂØÈü×¢ÉäÒº£¨ÉÌÆ·Ãû£º¸£¿£¿£¿£¿£¿ÉËÕ£©ÒÑ»ñÅúÉÏÊÐ £¬£¬£¬£¬£¬ÓÃÓÚÖÎÁƼÈÍù¾ÓÉÖÁÉÙ3ÏßÖÎÁƺóÏ£Íû£¨ÖÁÉÙʹÓùýÒ»ÖÖÂÑ°×øÌåÒÖÖƼÁ¼°ÃâÒßµ÷Àí¼Á£©µÄ¸´·¢»òÄÑÖÎÐԶ෢ÐÔ¹ÇËèÁö(RRMM)³ÉÈË»¼Õß¡£¡£¡£¡£¸ÃÒ©ÊÇÈ«ÇòÊ׸öÈ«ÈËÔ´°ÐÏòBCMAµÄCAR-Tϸ°ûÖÎÁƲúÆ· £¬£¬£¬£¬£¬Ò²ÊǺ£ÄÚµÚÒ»¿î×ÔÖ÷Ñз¢µÄÈ«Á÷³ÌÉú²úµÄϸ°ûÖÎÁƲúÆ·¡£¡£¡£¡£
¶à·¢ÐÔ¹ÇËèÁöÊÇѪҺϵͳ×î³£¼ûµÄ¶ñÐÔÖ×ÁöÖ®Ò» £¬£¬£¬£¬£¬ÔÚÎÒ¹úѪҺÖ×Áö·¢²¡ÂÊÖÐÅÅÃûµÚ¶þ £¬£¬£¬£¬£¬ÓÈÒÔÖÐÍíÄêÈËȺ½ÏΪ³£¼û¡£¡£¡£¡£ÏÖÔÚ £¬£¬£¬£¬£¬¶à·¢ÐÔ¹ÇËèÁö²¡ÒòδÃ÷ £¬£¬£¬£¬£¬ÎÞ·¨ÖÎÓú £¬£¬£¬£¬£¬¿ÉÑ¡ÔñµÄÖÎÁÆÊֶΰüÀ¨»¯ÁÆ¡¢ÒÆÖ²¡¢°ÐÏòÖÎÁÆ¡¢ÃâÒßÖÎÁÆµÈ £¬£¬£¬£¬£¬µ«¹Å°åÖÎÁƼƻ®ÁÆЧÓÐÏÞ £¬£¬£¬£¬£¬´ó´ó¶¼¹ÇËèÁö»¼ÕßÖÕ½«ÃæÁÙ¸´¾ÙÊÂÌâ¡£¡£¡£¡£¹Å°åÒ©ÎïÖÎÁÆÐè¶àÁƳÌÓÃÒ© £¬£¬£¬£¬£¬ºã¾ÃÖÎÁƸ±×÷ÓÃÔöÌí £¬£¬£¬£¬£¬µ¼Ö»¼ÕßÒÀ´ÓÐÔ½Ï²î £¬£¬£¬£¬£¬´Ó¶øÔÚÒ»¶¨Ë®Æ½ÉÏÓ°ÏìÁÆЧ¡£¡£¡£¡£Òò´Ë £¬£¬£¬£¬£¬¶à·¢ÐÔ¹ÇËèÁö¼±Ðè¸üºÃµÄÁÙ´²ÖÎÁƼƻ®¡£¡£¡£¡£
CAR-Tϸ°ûÁÆ·¨¿ÉΪ»¼ÕßÌṩ±ã½ÝµÄÒ»´ÎÐÔÊä×¢ £¬£¬£¬£¬£¬×èÖ¹ÁËÖظ´¸øÒ©´øÀ´µÄÖظ´¾ÍÒ½À§ÈÅ¡£¡£¡£¡£ÒÀ¸½ÌØÒìÐԺá¢É±ÉËÁ¦Ç¿µÄÓÅÊÆ £¬£¬£¬£¬£¬ÕâÖÖÁÆ·¨Îª¸´·¢»òÄÑÖÎÐԶ෢ÐÔ¹ÇËèÁö»¼Õß´øÀ´ÁËÊï¹â¡£¡£¡£¡£
¾ÝϤ £¬£¬£¬£¬£¬ÔÚ¸£¿£¿£¿£¿£¿ÉËÕ»ñÅúÇ° £¬£¬£¬£¬£¬È«Çò¹²ÓÐ8¿î»ñÅúÉÏÊеÄCAR-Tϸ°ûÖÎÁƲúÆ·£¨½öÓÐ2¿îÓÃÓÚÖÎÁƸ´·¢»òÄÑÖÎÐԶ෢ÐÔ¹ÇËèÁö£© £¬£¬£¬£¬£¬ÆäÖÐ6¿î²úÆ·µÄÑз¢ºÍ»ñÅúÉÏÊоùÔÚÃÀ¹ú £¬£¬£¬£¬£¬ÁíÍâ2¿î»ñÖйú¹ú¼ÒÒ©Æ·¼àÊÓÖÎÀí¾ÖÅú×¼µÄ²úÆ·Ò²Ô´ÓÚÃÀ¹ú¡£¡£¡£¡£´Ë´Î»ñÅúµÄ¸£¿£¿£¿£¿£¿ÉËÕÓÉѱ¹ÉúÎïÓëÐÅ´ïÉúÎïÅäºÏ¿ª·¢ £¬£¬£¬£¬£¬ÊÇÎÒ¹úÊ׿î×ÔÖ÷Ñз¢ÇÒ¾ßÓÐÈ«Á÷³ÌÉú²úÄÜÁ¦µÄCAR-Tϸ°ûÖÎÁƲúÆ· £¬£¬£¬£¬£¬ÓÐÍûΪÎÒ¹ú¸´¾ÙÊÂÖζ෢ÐÔ¹ÇËèÁö»¼Õß´øÀ´ÐµÄÖÎÁÆÑ¡Ôñ¡£¡£¡£¡£
ÃÀ¹úÁÙ´²Ö×Áöѧ»á£¨ASCO£©Öиüеĸ£¿£¿£¿£¿£¿ÉËÕÁÙ´²Ñо¿Ð§¹ûÏÔʾ £¬£¬£¬£¬£¬¸£¿£¿£¿£¿£¿ÉËÕ¾ßÓÐÓÅÒìµÄÓÐÓÃÐÔºÍÇå¾²ÐÔ¡£¡£¡£¡£ÁÙ´²ÊÔÑéÊý¾ÝÏÔʾ£º»¼Õ߿͹ۻº½âÂʺÍ×Ü»º½âÂÊ£¨ORR£©µÖ´ï96.0% £¬£¬£¬£¬£¬ÇÒ74.3%µÄ»¼ÕßʵÏÖ¡°¡ÝÍêÈ«»º½â¡±£¨CR)¡£¡£¡£¡£ÔÚÎÞCAR-TÖÎÁÆÊ·»¼ÕßÖÐ £¬£¬£¬£¬£¬ORRÔò¸ß´ï98.9% £¬£¬£¬£¬£¬ÇÒ78.7%µÄ»¼ÕßʵÏÖ¡°¡ÝCR¡±¡£¡£¡£¡£ÔÚÎÞÏ£ÍûÉúÑÄÆÚ£¨PFS£©·½Ãæ £¬£¬£¬£¬£¬»¼ÕßµÄ12¸öÔÂPFSÂÊΪ78.8% £¬£¬£¬£¬£¬ÎÞCAR-TÖÎÁÆÊ·»¼ÕßµÄ12¸öÔÂPFSÂʵִï84.4%¡£¡£¡£¡£ÔÚÇå¾²ÐÔ·½Ãæ £¬£¬£¬£¬£¬ÊÜÊÔ»¼ÕßµÄ3¼¶¼°ÒÔÉÏÃâÒßЧӦϸ°ûÏà¹ØÉñ¾¶¾ÐÔ×ÛºÏÕ÷±¬·¢ÂÊΪ0 £¬£¬£¬£¬£¬3¼¶¼°ÒÔÉÏϸ°ûÒò×ӷ籩±¬·¢Âʽö1.0%¡£¡£¡£¡£
